With applications going global and widely used in various regions, language adaptation is necessary. Developers build apps supporting different languages in the Windows platform using the MUI technology.
MUI is also known as Multilingual User Interface. These files are widely used in Windows OS to support multilingual applications and launch them with various languages in a single deployment. Starting from Windows 98 and up to the later Windows OS version, PCs can support more than 30 languages from the beginning.

Whenever a user changes the language, MUI files enable the switch. These files with .mui file extensions are found in the C drive and can easily be accessed if you use File Explorer Search.
How to Open and View MUI File Extension on Windows 10 or 11 Computer
Opening a MUI file depends on the type of file format you have. You will be able to open it using third-party application, viewer or where it was created. Some MUI files are part of the Windows MUI so it cannot be opened separately.
While there are ways you can view a .mui file, it is highly recommended not to open or delete it. MUI files are part of Windows internal application components and best left alone.